Junk no more
In the 1980s, people believed that 97 % of human DNA did nothing, thinking it was just “junk” left over from evolution. The logic was simple; “junk DNA” doesn’t code for proteins, so it must do nothing. It’s now clear that most DNA does have important functions, though we are still working out the finer details of these functions. Some of this supposed “junk” DNA is responsible for influencing the unique development of human brains. While much of the DNA used for protein coding in humans and apes are comparatively the same, there is significant variation in the surrounding DNA. An example of this can be seen in minisatellites, which are DNA strands with varying numbers of a short, repeated sequences of nucleotides. Fewer repeats of this sequence are found in a minisatellite near the human gene for a protein called ZNF558 than for apes’ minisatellites near this same gene. This shorter human minisatellite sequence influences production of the protein ZNF558, which results in it functioning in a different and unique manner in the development of the human brain. Protein coding genes are essential, but when the proteins are made, what they do and how they are put together leads to spectacular differences between organisms. DNA which was misunderstood as “junk” DNA plays a big role in these unique differences. What might other stretches of DNA be doing that our highly developed brains have yet to figure out? And what does this suggest about the mind of God, who designed our brains in the first place? Reference: https://www.cell.com/cell-stem-cell/pdf/S1934-5909(21)00384-2.pdf https://www.genengnews.com/news/human-and-chimp-brains-differ-in-non-coding-regulatory-dna/
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