From the general introduction:
"The origin of life is the most vexing problem facing contemporary science. It has fiercely resisted reductionist approaches to its resolution. All attempts to get life started solely through life's underlying chemistry have come up short. Could it be that although chemistry provides the medium for biological information, the information itself constitutes a message capable of riding free from the underlying medium? ... The contributors to this volume are not offering final answers. Rather, they are raising penetrating questions precisely where the old perspective has failed to offer a promising starting point for understanding the origin of biological information."